Publications

Coffee | Nov 3, 2024

Pre-print

  • Kehui Xiang, David P. Bartel. PAL-AI reveals genetic determinants that control poly(A)-tail length during oocyte maturation with relevance to human fertility. bioRxiv

Journal publications

    1. Jimmy Ly, Kehui Xiang, Kuan-Chung Su, Gunter B. Sissoko, David P. Bartel, Iain M. Cheeseman. Nuclear release of eIF1 globally increases stringency of start-codon selection to preserve mitotic arrest physiology. Nature (2024).
    1. Kehui Xiang, Jimmy Ly, David P. Bartel. Control of poly(A)-tail length and translation in vertebrate oocytes and early embryos. Developmental Cell 59, 1058-1074 (2024)
    1. Kehui Xiang, David P. Bartel. The molecular basis of coupling between poly (A)-tail length and translational efficiency. eLife 10:e66493 (2021).
    1. Hsin Jing-Ping, Kehui Xiang, James L. Manley. Function and control of RNA polymerase II CTD phosphorylation in vertebrate transcription and RNA processing. Molecular and Cellular Biology 34 2488-2498 (2014).
    1. Kehui Xiang, Liang Tong, James L. Manley. Delineating the structural blueprint of the pre-mRNA 3’ end processing machinery. Molecular and Cellular Biology 34, 1894-1910 (2014).
    1. Kehui Xiang, James L. Manley & Liang Tong. An unexpected binding mode for a Pol II CTD peptide phosphorylated at Ser7 in the active site of the CTD phosphatase Ssu72. Genes & Development 26, 2265-2270 (2012).
    1. Kehui Xiang, James L. Manley & Liang Tong. The yeast regulator of transcription protein Rtr1 lacks an active site and phosphatase activity. Nature Communications 3, 946 (2012).
    1. Jeong Ho Chang, Song Xiang, Kehui Xiang, James L. Manley & Liang Tong. Structural and biochemical studies of the 5’ to 3’ exoribonuclease Xrn1. Nature Structural & Molecular Biology 18, 270-276 (2011).
    1. Kehui Xiang, Takashi Nagaike, Song Xiang, Turgay Kilic, Maia M. Beh, James L. Manley, Liang Tong. Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex. Nature 467, 729-733 (2010).
    1. Chang Zhang, Yang Wu, Yuna Sun, Chuan Hong, Kehui Xiang, Yu Guo, Mark Bartlam & Zhiyong Lou. A novel non-radioactive assay for HIV-RT (RdDp) based on pyrosequencing for high-throughput drug screening. Protein Cell 1, 283-290 (2010).
    1. Zhiyong Lou, Yanhui Xu, Kehui Xiang, Nan Su, Lan Qin, Xu Li, George F. Gao, Mark Bartlam and Zihe Rao. Crystal structures of Nipah and Hendra virus fusion core proteins. FEBS Journal 273, 4538~4547 (2006).
    1. Kehui Xiang, Xingkun Ma, Huiyun Zhang, Weihong Mao. Making one-step rainbow hologram by the red-sensitive photopolymer plate. Physics Experimentation 193, 41~43 (2006, in Chinese).